Intrinsic Factors: William Bosworth Castle and the Development of Hematology and Clinical Investigation at Boston City Hospital Anand B. Karnad

ISBN: 9780674460805

Published: September 1st 1997

Hardcover

296 pages


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Intrinsic Factors: William Bosworth Castle and the Development of Hematology and Clinical Investigation at Boston City Hospital  by  Anand B. Karnad

Intrinsic Factors: William Bosworth Castle and the Development of Hematology and Clinical Investigation at Boston City Hospital by Anand B. Karnad
September 1st 1997 | Hardcover | PDF, EPUB, FB2, DjVu, audiobook, mp3, ZIP | 296 pages | ISBN: 9780674460805 | 6.71 Mb

In 1926, the attention of the medical world focused on Boston where George Richards Minot dramatically demonstrated that the feeding of liver to patients with pernicious anemia induced complete remission in that uniformly fatal disease.

But Minot,MoreIn 1926, the attention of the medical world focused on Boston where George Richards Minot dramatically demonstrated that the feeding of liver to patients with pernicious anemia induced complete remission in that uniformly fatal disease. But Minot, who won the Nobel Prize in Medicine or Physiology in 1934 for his achievement, did not progress beyond the development of a therapy: it remained for a young assistant at the Harvard Unit of the Boston City Hospital, William Bosworth Castle, to elucidate the pathogenesis of pernicious anemia.

Under Castles guidance, the Harvard Medical Unit at the Boston City Hospital became the Mecca for training in internal medicine as well as a world-renowned center for the study of the disorders of the blood, particularly the anemias and the diseases of the red cells. In Intrinsic Factors, Anand B. Karnad, a practicing hematologist, has captured the spirit and excitement of the Harvard Unit in all its components - patient care, research and teaching - and has described the many contributions to hematology that it produced. Karnad has balanced nonserious, even hilarious episodes and anecdotes with specific research accomplishments and inter-personal relationships which make good reading as well as capturing the spirit, enthusiasm and achievements of the Harvard Unit as it evolved under Castles inspired leadership.



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